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BIOCHEMICAL AND PHARMACOLOGICAL ACTIVITY OF NITROGEN HETEROCYLES

Contact :: orgachemweb@gmail.com

(Quinolines, Quinazolines, Quinoxalines, Benzoxazinones, Benzothiazinones, Dithiolanes, Benzothiazoles,  Benzoxazoles,  Triazoles , Thiazoles, Phthalazines etc).

--- Antibacterial
--- Antimalarial
--- Antineoplastic enhancers that potentiate the effect of anticancer drugs like vinblastine, adriamycine etc.,
--- Antiprotozoals.
--- Glutathione S-transferase inhibitors
--- Agents for the treatment of tissue damage due to inflammatory disorders and cancer
--- Cyclooxygenase type 2 (COX-2) inhibitors.
--- Antiglaucoma agents
--- Bronchodilators
--- Antiallergy and antiinflammatory agents, potent leukotriene antagonists.
--- Antiasthmatic agents with histamine -  antagonist activity.
--- HIV-1 Reverse transcriptase inhibitors
--- Agents for the treatment of hyperlipedemia, hypercholesterolemia, hyperglycemia, osteoporosis, obesity.
--- Hair growth promoter (Quinazolinone derivative for example)
--- to modulate the activity of both receptor and non receptor protein tyrosine kinases.
--- Antiulcer agents
Contact :: orgachemweb@gmail.com

    The Literature Survey is based on reports from:
--- Annual drug data report.
--- Drug data report.
--- Drugs for future.
--- Journal of medicinal chemistry and other journals and Patent search.
--- Annual reports in medicinal chemistry.
---Monographs  on natural products.

Based on the study, the  Synthesis and biological screening of various  nitrogen heterocycles with subsituents at various positions will be rewarding.
The new range of products included in our synthetic programme are several substituted derivatives  of these nitrogen heterocycles .

For further information contact: Contact:::

                                            Contact :: orgachemweb@gmail.com



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